Symbol
Name
ID

Rad50
RAD50 double strand break repair protein
MGI:109292

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Mouse Phenotypes

abnormal thymus morphology

spleen hyperplasia

decreased immature B cell number

increased late pro-B cell number

decreased pro-B cell number

decreased double-negative T cell number

anemia

impaired hematopoiesis

abnormal bone marrow cell morphology/development

decreased bone marrow cell number

absent bone marrow cell

thrombocytopenia

decreased B cell number

decreased pre-B cell number

decreased T cell number

decreased macrophage cell number

increased macrophage cell number

pancytopenia

abnormal hematopoietic stem cell morphology

abnormal CD4-positive, alpha beta T cell morphology

abnormal spleen morphology

abnormal hematopoietic system physiology

decreased IgE level

abnormal T-helper 1 physiology

abnormal T-helper 2 physiology

Availability

Mouse Genotype

Rad50^tm1Flv/Rad50^tm1Flv

Rad50^tm2Jpt/Rad50^tm2Jpt

Rad50^tm1Jpt/Rad50^tm2Jpt

Rad50^tm4.1Jpt/Rad50⁺

Rad50^tm1Jpt/Rad50^tm3Jpt
Tg(Mx1-cre)1Cgn/0 (conditional)

Rad50^tm2.1Flv/Rad50^tm2.2Flv
Tg(Cd4-cre)1Cwi/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23